Evidence map›Paper›PMID 42146396›Full record

ArticlebioRxiv : the preprint server for biology2026

Growth-dependent tRNA Reprogramming and Codon Bias Link Translation to Metabolic State in

Michelle M Mitchener, Caleb M Anderson, Mark Veleba, Kayla Teo, Mélanie Roch, Ruixi Chen, Yifeng Yuan, Isaiah Han, Agnieszka Dziergowska, Kevin Pethe and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Michelle M MitchenerAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.ORCID 0000-0001-5036-2286
Caleb M AndersonDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland.ORCID 0000-0003-3395-7805
Mark VelebaSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore 637551, Singapore.ORCID 0000-0002-9516-8660
Kayla TeoAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.
Mélanie RochDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland.ORCID 0000-0001-6485-8434
Ruixi ChenDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Yifeng YuanDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-9549-2698
Isaiah HanAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.ORCID 0009-0003-8915-2165
Agnieszka DziergowskaInstitute of Organic Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.ORCID 0000-0002-8888-380X
Kevin PetheAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.ORCID 0000-0003-0916-8873
Thomas J BegleyDepartment of Biological Sciences, University at Albany, Albany, NY 12222, USA.ORCID 0000-0002-5641-7644
Kimberly A KlineAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.ORCID 0000-0002-5472-3074
Peter C DedonAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore 138602, Singapore.ORCID 0000-0003-0011-3067

Funding

Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodelsR01ES026856 · NIEHS · SUNY POLYTECHNIC INSTITUTE · PI Thomas J Begley, Peter C Dedon · 2016 to 2026
$3.9M
Chemical Modifications to Wobble Uridines in tRNA Regulate Responses to StressR01GM143749 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI BEGLEY, THOMAS J, SHENG, JIA · 2022 to 2025
$1.4M
NIEHS NIH HHS R01 ES026856NIGMS NIH HHS R01 GM143749
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42146396
PMCPMC13174587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.