Evidence map›Paper›PMID 42146369›Full record

ArticlebioRxiv : the preprint server for biology2026

Human placental trophoblasts support sustained

Eliza R McColl, Diane G Edmondson, Bridget D DeLay, Karan G Kaval, Steven J Bark, Steven J Norris, Indira U Mysorekar

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eliza R McCollDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.
Diane G EdmondsonDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center Houston, Houston, TX, USA.
Bridget D DeLayDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center Houston, Houston, TX, USA.
Karan G KavalDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center Houston, Houston, TX, USA.
Steven J BarkDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.
Steven J NorrisDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center Houston, Houston, TX, USA.
Indira U MysorekarDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-3917-8677

Funding

Factors Affecting longterm in vitro culture of Treponema pallidumR01AI141958 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Diane G Edmondson, STEVEN J. NORRIS · 2018 to 2026
$3.9M
Mechanisms of tunneling nanotube formation by ZIKV NS1 in viral host interactions at the maternal-fetal interfaceR01AI176505 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI Joyce Jose, Indira U Mysorekar · 2024 to 2026
$2.3M
HIGH THROUGHPUT NGS SEQUENCER AT THE BCM GENOMIC AND RNA PROFILING CORES10OD036427 · OD · BAYLOR COLLEGE OF MEDICINE · PI KRAUSHAAR, DANIEL · 2024 to 2024
$600k
Exploring T. pallidum Pathogenesis in the Placenta Using Novel In Vitro Models of Syphilis During PregnancyR21AI194017 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MYSOREKAR, INDIRA U · 2025 to 2025
$452k
NIAID NIH HHS R01 AI141958NIAID NIH HHS R01 AI176505NIAID NIH HHS R21 AI194017NIH HHS S10 OD036427
6 · The paper itself

Abstract

Congenital syphilis is a leading cause of preventable stillbirth, yet the mechanisms that enable

Indexed as

bacterial spirochetescholesterol synthesismaternal-fetal interfaceSf1EpType 1 interferon

Identifiers

PMID42146369
PMCPMC13174412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.