Evidence map›Paper›PMID 42146355›Full record

ArticlebioRxiv : the preprint server for biology2026

Conserved principles of central carbon partitioning in Hippo-Yorkie-driven

Younshim Park, Mujeeb Qadiri, John M Asara, Yanhui Hu, Norbert Perrimon

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Younshim ParkDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-6364-2383
Mujeeb QadiriDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0009-0006-9697-6447
John M AsaraDepartment of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Yanhui HuDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1494-1402
Norbert PerrimonDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7542-472X

Funding

Investigating metabolic responses to high sugar diets and the onset of diabetic phenotypesR01DK136945 · NIDDK · TRUSTEES OF INDIANA UNIVERSITY · PI Angelo D'Alessandro, NORBERT PERRIMON · 2023 to 2026
$2.4M
CANCAN ? CORNELLOT2CA278685 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GONCALVES, MARCUS DASILVA · 2022 to 2023
$657k
NCI NIH HHS OT2 CA278685NIDDK NIH HHS R01 DK136945
6 · The paper itself

Abstract

Central carbon metabolism undergoes extensive remodeling in cancers, yet the extent to which the resulting network architectures and operating principles are conserved across species and oncogenic contexts in vivo remains unclear. Here, central carbon metabolism was evaluated in Hippo/Yki-driven

Identifiers

PMID42146355
PMCPMC13174419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.