Evidence map›Paper›PMID 42146351›Full record

ArticlebioRxiv : the preprint server for biology2026

MilliMap: interactive closed-loop analysis for spatial omics.

Qianlu Feng, Siyuan Brant Qian, Lily Jiaxin Wan, Zachary Starr, Sarah Asif, Hee-Sun Han

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qianlu FengNeuroscience Program, University of Illinois Urbana-Champaign.ORCID 0009-0001-9790-3497
Siyuan Brant QianSiebel School of Computing and Data Science, University of Illinois Urbana-Champaign.ORCID 0009-0007-9574-8423
Lily Jiaxin WanElectrical and Computer Engineering, University of Illinois Urbana-Champaign.ORCID 0000-0001-8006-0019
Zachary StarrDepartment of Molecular and Cellular Biology, University of Illinois Urbana-Champaign.
Sarah AsifNeuroscience Program, University of Illinois Urbana-Champaign.ORCID 0009-0006-9831-3436
Hee-Sun HanNeuroscience Program, University of Illinois Urbana-Champaign.ORCID 0000-0003-3616-291X

Funding

Chemical toolbox for multiscale, integrative imaging: Connecting cellular gene expression to organ-scale phenotypeR35GM147420 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Hee-Sun Han · 2022 to 2026
$2.2M
NIGMS NIH HHS R35 GM147420
6 · The paper itself

Abstract

Spatial omics analysis requires iterative interplay between statistical computation and tissue-context interpretation, yet current workflows fragment these steps across disconnected environments. We present MilliMap, an interactive framework that unifies statistical analysis with spatial exploration. By closing the analysis-visualization loop, MilliMap empowers biologists to steer parameters, refine ROIs, and validate findings within a single environment. We demonstrate its utility by delineating complex neuroanatomy and identifying niche-restricted functional states in tumor microenvironments.

Identifiers

PMID42146351
PMCPMC13174364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.