Evidence map›Paper›PMID 42146327›Full record

ArticleOpen forum infectious diseases2026

Molnupiravir Treatment Associated With Clearance of Cache Valley Virus From Cerebrospinal Fluid in an Immunocompromised Child With Meningoencephalitis.

Destini Smith Byrd, Amitha Ananth, Claire McDonald, T Prescott Atkinson, Charles Y Chiu, David W Kimberlin, Lydia Marcus

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Destini Smith ByrdDepartment of Pediatrics, Vanderbilt University, Nashville, Tennessee, USA.
Amitha AnanthDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Claire McDonaldDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
T Prescott AtkinsonDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Charles Y ChiuDepartment of Medicine, University of California, SanFrancisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-2915-2094
David W KimberlinDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Lydia MarcusDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-2725-2825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cache Valley virus is a bunyavirus endemic to North America, commonly infecting livestock, but known to cause meningoencephalitis in immunocompromised humans in rare cases. We present the first known pediatric case of Cache Valley virus encephalitis in an adolescent with IKZF1/Ikaros immunodeficiency with viral clearance from cerebrospinal fluid after molnupiravir antiviral therapy.

Indexed as

cache valley virusencepahlitisimmunodeficiencyPediatric

Identifiers

PMID42146327
PMCPMC13175980

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.