ArticleJOR spine2026
Lifetime Physical Loading and Magnetic Resonance-Derived Intervertebral Disc Health in Adults With Chronic Low Back Pain: A Cross-Sectional Study.
Article in JOR spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The intervertebral disc (IVD) is a mechanosensitive structure influenced by physical loading (physical activity/sport/exercise); however, the optimal type and parameters of physical loading for IVD health remain unclear. The Bone Physical Activity Questionnaire is validated to predict bone mineral density from lifetime exposure to physical loading; therefore, we explored the association between lifetime physical loading and IVD health. Methods: This cross-sectional study recruited 40 individuals with chronic low back pain. Outcomes were magnetic resonance imaging-derived IVD measures reported as both averages and across individual spinal levels T11/T12-L5/S1, including T2 (ms, measure of hydration), height-to-vertebral-body ratio, nucleus-to-annulus signal intensity ratio, volume (cm Results: Lifetime bone-related physical loading was not associated with IVD health across average spine values, except nucleus-to-annulus signal intensity ratio, which was negatively associated ( Conclusions: Physical activity loading necessary for improved IVD health appears to differ from loading previously reported for optimal bone health. Specifically, lifetime activity levels considered beneficial for bone were associated with less favourable L5/S1 IVD characteristics, highlighting distinct loading requirements across these tissues. Future studies could develop a questionnaire that captures optimal physical loading for IVD health, such as moderate physical loading.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.