ArticleACS omega2026
Isoxazole Derivative Induces Apoptosis-like Death and Autophagy through Oxidative Stress in
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Leishmaniasis is one of the most important neglected tropical diseases and a significant global health burden, affecting millions of people worldwide. The limitations of current treatments, including toxicity, high cost, and the emergence of drug resistance, underscore the urgent need for new antileishmanial agents. Isoxazoles are a versatile class of heterocyclic compounds with documented antiparasitic activity, making them attractive scaffolds for drug development. In this study, we synthesized and evaluated a new isoxazole derivative, 4-[((4-fluorophenyl)-amino)-methyl]-5-(4-nitrophenyl)-3-[(2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.