Evidence map›Paper›PMID 42146234›Full record

ArticleACS omega2026

Bromochloroacetonitrile Cytotoxicity and Regenerative Responses in HaCaT and HUVEC Cells.

Elif Fayadoglu, Mustafa Fayadoglu, Banu Barutca, A Tansu Koparal, A Savas Koparal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elif FayadogluInstitute of Graduate Programs Department of Biology, Programme of Molecular Biology, Eskişehir Technical University, Tepebaşı, Eskişehir 26470, Turkey.
Mustafa FayadogluBiotechnology Institute, Ankara University, Ankara 06135, Turkey.
Banu BarutcaYunus Emre Vocational School of Health Services, Department of Medical Services and Techniques, Anadolu University, Eskişehir 26470, Turkey.
A Tansu KoparalYunus Emre Vocational School of Health Services, Department of Medical Services and Techniques, Anadolu University, Eskişehir 26470, Turkey.ORCID https://orcid.org/0000-0001-8201-6708
A Savas KoparalYunus Emre Vocational School of Health Services, Department of Medical Services and Techniques, Anadolu University, Eskişehir 26470, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bromochloroacetonitrile (BCAN) is a halogenated nitrogenous disinfection byproduct (N-DBP) frequently detected in chlorinated swimming pools. While its cytotoxicity has been established in various mammalian cells, its dermal and vascular impacts remain poorly understood. This study evaluated the cytotoxic, oxidative, and regenerative responses of human keratinocytes (HaCaT) and vascular endothelial cells (HUVECs) to BCAN exposure in vitro. BCAN significantly reduced HaCaT viability in a concentration- and time-dependent manner, with an IC

Identifiers

PMID42146234
PMCPMC13177220

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.