Conjugated Polymeric Nanostructures as Potential Tools in DNA Nanotechnology: Interactions with the Double Helix.

Rayane M de Oliveira, Caio H V da Silva, Mariana P Brandão, Andreza G S Subtil, Márcio S Rocha

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Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Rayane M de OliveiraDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.

Caio H V da SilvaDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.

Mariana P BrandãoDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.

Andreza G S SubtilDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.

Márcio S RochaDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0000-0003-0323-3718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We synthesized two types of conjugated polymeric nanoparticles (CPNs), made with MEH-PPV (poly-[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene]) and PFD (poly-(9,9-di-n-dodecyl fluorenyl-2,7-diyl)), that significantly interact with double-stranded DNA. The binding between these nanostructures and the biopolymer was characterized via single-molecule force spectroscopy assays performed by optical tweezers and by direct visualization via atomic force microscopy imaging. The results show that both types of CPNs bind cooperatively outside the double helix, inducing bending, and with a considerably high equilibrium association constant, on the order of 10

Identifiers

PMID42146189

DOI10.1021/acsomega.5c11640

PMCPMC13176981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.