ArticleFrontiers in oral health2026
Presence of bacterial DNA in synovial fluid from the temporomandibular joint in patients with temporomandibular joint disorders.
Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
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4 authors.
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Abstract
Introduction: Temporomandibular joint disorders (TMJD) are common, affecting approximately 30% of the population. While the aetiology of TMJD has been considerably discussed, one aspect that has not been thoroughly investigated is the potential occurrence and role of bacteria in the temporomandibular joint (TMJ). This study aimed to determine the existence of bacteria in the TMJ synovial fluid of patients with TMJD. Methods: In this cohort study, synovial fluid from patients with TMJD, was collected during routine surgery at the Oral and Maxillofacial Unit at Karolinska University Hospital, Stockholm. Data analysis of the bacterial 16S rRNA sequencing was performed using automated cloud-based EPI2ME workflows (Oxford Nanopore Technologies). Results: The synovial fluid of 64 patients (mean age 41 years), of whom 86% ( Conclusion: The findings of this study indicate that bacterial presence within the TMJ seems frequent and demonstrates diagnostic clustering, that warrant further investigation. However, the results should be interpreted with caution because of the high sensitivity of 16S rRNA sequencing.
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