Evidence map›Paper›PMID 42146120›Full record

ArticleInternational journal of dentistry2026

Enamel Microhardness of Resin-Infiltrated White Spot Lesions After Bleaching With and Without ACP: An In Vitro Study.

Pauravi Hegde, Shashi Rashmi Acharya, Arun Mayya, Kundabala Mala, Sandya Kini

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Article in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pauravi HegdeDepartment of Conservative Dentistry and Endodontics, DY Patil School of Dentistry, DY Patil (Deemed to be) University, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0002-6287-0947
Shashi Rashmi AcharyaDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India, manipal.edu.ORCID https://orcid.org/0000-0001-8906-6353
Arun MayyaDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India, manipal.edu.ORCID https://orcid.org/0000-0002-7230-3479
Kundabala MalaDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India, manipal.edu.ORCID https://orcid.org/0000-0003-2407-1877
Sandya KiniDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India, manipal.edu.ORCID https://orcid.org/0000-0002-9443-2335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: White spot lesions (WSLs) represent the earliest clinical manifestations of enamel demineralization. Resin infiltration (RI) is a minimally invasive method used to mask WSLs for esthetic improvement; however, infiltrated enamel may remain prone to staining and surface degradation. Carbamide peroxide bleaching agents have been reported to reduce enamel microhardness, while the inclusion of remineralizing components such as amorphous calcium phosphate (ACP) may mitigate these effects. Objectives: To compare the microhardness of resin-infiltrated enamel with artificial WSLs following the application of 22% carbamide peroxide bleaching systems with and without ACP. Methods: Thirty extracted noncarious maxillary premolars were prepared with artificial WSLs and treated with RI. The samples were randomly divided into three groups ( Results: One-way ANOVA revealed a statistically significant difference in microhardness among the three groups ( Conclusion: Bleaching agents containing 22% carbamide peroxide, particularly when combined with ACP, were associated with higher posttreatment microhardness compared with the RI-only group.

Indexed as

amorphous calcium phosphatecarbamide peroxidedental bleachingdental enamelmicrohardnessremineralizationresin infiltrationtooth demineralizationVickers hardness testwhite spot lesions

Identifiers

PMID42146120
PMCPMC13173756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.