ArticleFrontiers in cellular and infection microbiology2026
Vitamin D metabolites reshape bovine mammary epithelial responses relevant to mastitis through host-directed mechanisms.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Bovine mastitis remains one of the most prevalent diseases in dairy cattle and is largely managed through antibiotic therapy, which contributes to antimicrobial resistance. Host-directed strategies that enhance mammary epithelial defenses may complement conventional treatments. Although vitamin D Methods: Antimicrobial and antibiofilm activity were assessed against mastitis-associated Results: D and 25D were well tolerated by MAC-T cells. They exhibited limited antimicrobial or antibiofilm activity, but pretreatment of the cells with 25D significantly reduced Conclusion: The findings indicate that vitamin D
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