ReviewFrontiers in nutrition2026
Engineering biopolymer nanoparticles for targeted nanomedicine in cancer therapy and food preservation.
Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from chitosan and other carbohydrates, have emerged as versatile platforms capable of addressing these limitations in both biomedical and food systems. This review provides a comprehensive overview of the design, engineering, and surface functionalization of nanoparticles, highlighting their physicochemical properties, formulation strategies, and mechanisms governing stability, encapsulation efficiency, and controlled release. In the biomedical context, these nanocarriers have shown considerable promise for targeted cancer therapy by improving drug bioavailability, enhancing cellular uptake, enabling receptor-mediated targeting, and reducing systemic toxicity. Advances in ligand-mediated surface functionalization, active targeting strategies, and stimuli-responsive delivery systems are discussed, together with current progress in preclinical and clinical development of nanomedicines. At the same time, carbohydrate-based nanoparticles are increasingly explored in food science as delivery systems for bioactive compounds, antimicrobial agents, and natural preservatives, where they contribute to improved food stability, extended shelf life, and protection of sensitive nutrients. By integrating perspectives from nanomedicine and food technology, this review highlights the multifunctional potential of chitosan and carbohydrate-derived nanomaterials as sustainable and biocompatible platforms for controlled delivery in both therapeutic and food preservation applications. Critical challenges related to large-scale production, stability, regulatory considerations, and translational feasibility are also examined. Overall, advances in nanoparticle engineering and surface functionalization may enable the development of next-generation biopolymer nanocarriers with broad applications spanning targeted cancer therapy and innovative food preservation technologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.