Evidence map›Paper›PMID 42145944›Full record

ArticleGut microbes reports2026

Safety and efficacy concerns in Indian probiotics: Insights from whole-genome sequencing and

Irulappan Madhumathi, Vishnukumar Ramesh, Boomiga Rathakrishnan, Baby Abirami, Karthik Gunasekaran, T Sathish Kumar, Priyadharshini Jeyasankar, Gunachandru Raja, Karnan Selvam, Subbulakshmi Rajendran and 3 more

Abstract read
In one paragraph

Article in Gut microbes reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Irulappan MadhumathiDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Vishnukumar RameshDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Boomiga RathakrishnanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Baby AbiramiDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Karthik GunasekaranDepartment of General Medicine, Christian Medical College, Vellore, India.
T Sathish KumarDepartment of Paediatrics, Christian Medical College, Vellore, India.
Priyadharshini JeyasankarDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Gunachandru RajaDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Karnan SelvamDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Subbulakshmi RajendranDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Ayyanraj NeeraviDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Kamini WaliaDivision of Descriptive Research, Indian Council of Medical Research, New Delhi, India.
Balaji VeeraraghavanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.ORCID https://orcid.org/0000-0002-8662-4257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute diarrhea remains a major public health challenge in India, particularly among children, where probiotics are commonly used as adjunctive therapy. However, concerns regarding the quality, safety, and regulatory oversight of commercial probiotic formulations persist. This study evaluated 13 probiotic products marketed in India for antibiotic susceptibility, gastrointestinal survivability, and safety. A combined

Indexed as

acute diarrheaantimicrobial resistanceIndiaProbioticsquality controlregulatory oversightSaccharomyces boulardii

Identifiers

PMID42145944
PMCPMC13178174

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.