Evidence map›Paper›PMID 42145942›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2026

A multi-channel fluorescence endoscope for pre-operative assessment of epithelial ovarian cancer.

Sanjana Pannem, Jonathan Elliott, Keith Paulsen, Kimberley S Samkoe

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanjana PannemThayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.
Jonathan ElliottGeisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.
Keith PaulsenThayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.
Kimberley S SamkoeThayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.

Funding

Molecular Fluorescence-Guided Surgery PlatformR01CA167413 · NCI · DARTMOUTH COLLEGE · PI PAULSEN, KEITH D., SAMKOE, KIMBERLEY · 2013 to 2025
$5.7M
Paired-agent imaging for resection during surgery (PAIRS) for head & neck cancersR37CA212187 · NCI · DARTMOUTH-HITCHCOCK CLINIC · PI SAMKOE, KIMBERLEY · 2018 to 2024
$2.7M
Pre-operative Paired Agent Assessment for Cytoreduction of Epithelial Ovarian CancerF31CA295076 · NCI · DARTMOUTH COLLEGE · PI Sanjana Pannem · 2025 to 2026
$50k
NCI NIH HHS F31 CA295076NCI NIH HHS R01 CA167413NCI NIH HHS R37 CA212187
6 · The paper itself

Abstract

Determining if a patient with epithelial ovarian cancer is eligible for surgical resection is difficult due to late-stage diagnosis and metastases. This often leads to patients receiving unnecessary surgery and delays in adjuvant therapies; thereby, increasing healthcare costs and decreasing therapeutic efficacy. We aim to utilize Paired Agent Imaging (PAI), a fluorescence molecular imaging technique, to pre-operatively assess tumor burden and determine an individual's eligibility for surgery. We developed a multi-channel optical endoscope with PAI to enhance tumor visualization and guide treatment planning. The system is tested on fluorescent dye solutions to evaluate its linear detection range and system sensitivity to fluorophore concentration.

Indexed as

EndoscopefluorescenceMulti-channelOvarian cancerpre-operative imaging

Identifiers

PMID42145942
PMCPMC13175120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.