ReviewMolecular imaging
Imaging Sphingosine-1-Phosphate Receptor: A Promising Strategy to Neuroinflammation of Epilepsy.
Review in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
Abstract
Epilepsy is a complex neurological disorder characterized by recurrent, unprovoked seizures. Emerging evidence indicates that the sphingosine-1-phosphate receptor (S1PR) family plays a significant and multifaceted role in the pathological processes underlying epileptogenesis and blood-brain barrier integrity. This review comprehensively explores the intricate role of S1PR signaling in epilepsy, with a particular focus on the integration of neuroimaging findings. In this review, we summarize recent advances in Positron Emission Tomography techniques that offer invaluable insights into S1PR-related pathophysiological changes in the epileptic brain. Furthermore, we discuss the substantial potential of S1PRs as novel therapeutic targets. By integrating these cutting-edge neuroimaging biomarkers with our evolving understanding of the underlying molecular pathways, this review aims to highlight promising new diagnostic tools and innovative treatment strategies for epilepsy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.