Evidence map›Paper›PMID 42145870›Full record

ArticleClinical, cosmetic and investigational dermatology2026

Comparative Evaluation of Buffy Coat-Derived and Apheresis Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia: Laboratory and Clinical Insights.

Chunru Huang, Minhua Wu, Yuyuan Li, Xiaogen Tang, Miaochan Chen, Wenli Li, Qifeng Liu, Kui Cai

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In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chunru HuangDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Minhua WuDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Yuyuan LiDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Xiaogen TangDepartment of Transfusion Medicine, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Miaochan ChenDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Wenli LiDepartment of Dermatology, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Qifeng LiuDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.
Kui CaiDepartment of Blood Transfusion, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Androgenetic alopecia (AGA) is the most common type of hair loss, and platelet-rich plasma (PRP) has emerged as a promising therapy. However, preparation methods may influence clinical outcomes. Objective: To compare buffy coat and apheresis PRP in terms of laboratory characteristics and treatment efficacy in AGA, and to identify predictors of response. Methods: A retrospective analysis was conducted on 747 PRP preparations (514 buffy coat, 233 apheresis) and 163 AGA patients who were eligible for final analysis after screening (87 buffy coat, 76 apheresis). Laboratory indices and PRP parameters were assessed. Clinical efficacy was evaluated by trichoscopy and patient-reported outcomes. Logistic regression was used to determine independent predictors. Results: Apheresis PRP required greater blood volumes and yielded higher platelet concentration (1242×10 Conclusion: Both buffy coat and apheresis PRP are effective for AGA. Buffy coat PRP was associated with greater subjective improvement despite lower platelet counts, suggesting that platelet number alone does not determine efficacy. Repeated treatments significantly enhance outcomes, highlighting the importance of treatment frequency in PRP therapy.

Indexed as

androgenetic alopeciaapheresisbuffy coatplatelet-rich plasma

Identifiers

PMID42145870
PMCPMC13179800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.