ArticleClinical, cosmetic and investigational dermatology2026
Bidirectional Mendelian Randomization Suggests Causal Effects of 731 Immunophenotypes on Vitiligo Pathogenesis.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This two-sample Mendelian randomization (MR) study aimed to investigate the causal relationship between 731 immune cell traits and vitiligo. Patients and Methods: Genetic variants with genome-wide suggestive significance ( Results: The onset of vitiligo was significantly associated with reduced levels of TD CD4 Conclusion: We suggest novel causal links between vitiligo and specific immune cell dysregulation, highlighting the pivotal role of adaptive immunity in pathogenesis and informing potential therapeutic targets such as TD CD4
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