Evidence map›Paper›PMID 42145821›Full record

ReviewFood science & nutrition2026

Unlocking the Bioactivity of Cyperi Rhizoma as a Functional Food: Insights From Culinary Processing and Herb Combinations.

Yuehan Liu, Liyuan Xu, Liting Lin, Maoyuan Jiang, Wan Liao, Tianhui Gao

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuehan LiuSchool of Pharmacy Qilu Medical University Zibo Shandong China.
Liyuan XuSchool of Pharmacy Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China.
Liting LinSchool of Pharmacy Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China.
Maoyuan JiangSchool of Pharmacy Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China.
Wan LiaoSchool of Pharmacy Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China.
Tianhui GaoSchool of Pharmacy Qilu Medical University Zibo Shandong China.ORCID https://orcid.org/0009-0001-6451-0582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyperi Rhizoma (CR), a globally invasive weed threatening major crops, paradoxically represents an underutilized resource for sustainable nutraceutical development. In order to transform this agricultural pest into a viable functional food ingredient, this review explores how culinary-inspired processing (vinegar, wine, salt, etc.) and food-compatible botanical pairings synergistically enhance the bioactivity of CR. We demonstrate that traditional processing deglycosylates flavonoids and modulates volatile oils, boosting bioavailability and analgesic, antidepressant efficacy validated in vivo. Herb pairs with food-medicines generate novel metabolites and amplify bioactivity, as exemplified by the CR-Alpiniae Officinarum Rhizoma herb pair that promotes gastric ulcer inhibition via gut barrier repair. Moreover, CR-based formulations show clinical success in digestive/neurological disorders. This work connects weed control strategies with value-added food uses, including spice blends and nanoparticle-encapsulated supplements, establishing the scientific basis for transforming CR into scalable, culturally adapted functional foods. These innovations target global health needs while reducing agricultural damage caused by this invasive plant.

Indexed as

agricultural byproduct upcyclingbiological activity mechanismCyperi Rhizomaherb‐food synergy

Identifiers

PMID42145821
PMCPMC13178274

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.