ReviewAmerican journal of lifestyle medicine2026
A Review of the Effects of Lifestyle Factors on Skin Aging.
Review in American journal of lifestyle medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin aging reflects both intrinsic biological processes and cumulative lifestyle behaviors. While lifestyle medicine pillars are well established in cardiometabolic disease prevention, their relevance to dermatologic aging is increasingly supported by evidence. This narrative review synthesized human observational studies, randomized trials, and preclinical models examining the effects of nutrition, physical activity, psychological stress, sleep, substance use, and social connection on skin aging. Outcomes included visible aging phenotypes, barrier function, dermal structure, inflammatory signaling, oxidative stress, mitochondrial function, and cellular senescence. Plant-predominant, antioxidant-rich diets were associated with fewer wrinkles, improved hydration, and reduced atrophy. High-sugar and high-salt diets accelerated senescence and extracellular matrix damage in preclinical models. Regular exercise promoted dermal thickness, collagen synthesis, and reduced inflammatory signaling. Chronic stress and poor sleep impaired barrier recovery, reduced collagen-related gene expression, and accelerated visible aging. Tobacco, heavy alcohol, and stimulant use were strongly linked to premature aging through oxidative stress, inflammation, and microvascular injury. Social isolation was associated with elevated systemic inflammation, suggesting indirect relevance to skin aging. Lifestyle behaviors are consistently associated with skin aging physiology and appearance. Longitudinal and interventional studies are needed to clarify causality and guide dermatologic practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.