ArticleFrontiers in medicine2026
Development of a risk prediction model for adhesive intestinal obstruction following laparoscopic surgery for acute appendicitis based on clinical characteristics and laboratory indicators.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Adhesive intestinal obstruction (AIO) is a recognized complication following laparoscopic surgery for acute appendicitis (AA), although its overall incidence remains relatively low. This study aimed to develop a risk prediction model based on clinical characteristics and laboratory indicators to facilitate early identification and prevention of postoperative AIO. Methods: In this retrospective cohort study, 298 AA patients who underwent laparoscopic surgery between January 2020 and November 2024 were enrolled. Patients were categorized into AIO ( Results: Compared with the non-AIO group, the AIO group exhibited significantly longer disease duration, a higher prevalence of systemic inflammatory response syndrome (SIRS), elevated white blood cell count (WBC), increased neutrophil-to-lymphocyte ratio (NLR), and lower albumin (ALB) levels ( Conclusion: Disease duration, SIRS, WBC, NLR, and ALB are significantly associated with AIO occurrence after laparoscopic appendectomy. The developed prediction model effectively stratifies postoperative AIO risk in AA patients, potentially assisting clinicians in implementing timely preventive measures and reducing AIO incidence.
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