ArticlemedRxiv : the preprint server for health sciences2026
Perceptions of HPV Self-Collection for Cervical Cancer Screening Among Mobile Health Program Attendees.
Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: Mobile health programs (MHPs) provide essential preventive services to uninsured and underserved communities. Following the 2024 regulatory approval of human papillomavirus (HPV) self-collection for cervical cancer screening, MHPs represent an access point for healthcare-based self-collection. However, little is known about patient perceptions of this approach in MHP and other healthcare settings. Methods: From May - August 2025, we surveyed individuals aged 25-65 years with a cervix who attended MHPs in Southern Arizona. The survey assessed interest in HPV self-collection, preferred locations, instructional preferences, and facilitators to attend follow-up after a positive result. Descriptive statistics summarized demographic characteristics and survey responses. Results: Fifteen female participants completed the survey (mean age 36 years). Ten (67%) identified as Hispanic or Latino, nine (60%) preferred Spanish, and 14 (93%) were uninsured. Interest in HPV self-collection was high, with ten (67%) very or extremely interested. Among those interested, nine (69%) preferred home-based self-collection, and four (31%) preferred clinic or MHP-based self-collection. Most common concerns regarding self-collection on the MHP were ensuring privacy (n=7; 47%) and knowing how to perform the test correctly (n=5; 33%). Most participants (n=11; 73%) reported being very or extremely confident they would attend follow-up after a positive result; language-concordant support, reminder calls, and scheduling assistance were the most endorsed facilitators. Conclusion: HPV self-collection was highly acceptable among MHP attendees, although home-based self-collection was most preferred. Addressing privacy concerns, providing multiple modes of instruction, and offering navigation support may improve implementation success and ensure timely follow-up care in MHP settings.
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