ArticleJournal of dental research, dental clinics, dental prospects2025
Effect of single and repeated potassium iodide applications versus glutathione on silver diamine fluoride-induced tooth discoloration in primary teeth: An in vitro comparative study.
Article in Journal of dental research, dental clinics, dental prospects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride-induced discoloration.European oral research · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Background: This study aimed to evaluate the effects of a single application of potassium iodide (KI), repeated daily applications of KI, and glutathione (GSH) on silver diamine fluoride (SDF)-induced tooth discoloration in primary canines. Methods: This in vitro study was performed on 36 extracted primary canines with dentinal caries, which were randomly assigned to four treatment groups: A (38% SDF alone), B (38% SDF+immediate single application of KI), C (38% SDF+repeated daily KI applications), and D (38% SDF+20% GSH). Color changes were measured at baseline and after 1, 14, and 30 days using a spectrophotometer and the CIEL*a*b* system. Statistical analysis included one-way ANOVA with post hoc Tukey tests for inter-group comparisons, and repeated-measures ANOVA with Bonferroni's correction for intra-group comparisons. Results: Significant differences in tooth discoloration (ΔE) were observed between the study groups at all time intervals ( Conclusion: Repeated daily applications of KI or GSH effectively reduced SDF-induced tooth discoloration in primary canines. GSH showed the most favorable esthetic outcomes, suggesting its potential as a promising adjunct to SDF.
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Registered trials
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