Evidence map›Paper›PMID 42145407›Full record

ArticleBioinformation2026

Effect of premixed and sequential intrathecal fentanyl on spinal block characteristics.

Priyanka Gupta, Utsav Sharma, Deepak Gupta, Lokesh Bansal, Payal Jain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Priyanka GuptaDepartment of Anesthesiology, S.R.V.S Medical College, Shivpuri, Madhya Pradesh, India.
Utsav SharmaDepartment of Anaesthesiology, DR Laxminarayan Pandey Government Medical College, Ratlam, India.
Deepak GuptaDepartment of Anaesthesiology, DR Laxminarayan Pandey Government Medical College, Ratlam, India.
Lokesh BansalDepartment of Anaesthesiology, Indraprastha Apollo Hospital, New Delhi, India.
Payal JainDepartment of Anaesthesiology, ESIC Medical College & Hospital, Faridabad.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal method of intrathecal fentanyl administration with hyperbaric bupivacaine remains uncertain, as premixed and sequential techniques may influence block characteristics differently. In this prospective observational comparative study, 42 ASA I-II adults (21 per group) received fentanyl 0.5 ml with hyperbaric bupivacaine 2.5 ml either premixed or sequentially. Sequential administration produced faster sensory onset at T10 (5.00±1.37 vs 6.48±1.32 min) and motor onset (6.10±1.37 vs 8.00±1.30 min) with longer sensory and motor regression times. Time to first rescue analgesia was also longer (205.33±12.08 vs 175.38±14.41 min), suggesting earlier onset and prolonged block with the sequential technique.

Indexed as

hyperbaric bupivacaineIntrathecal fentanylpremixed techniqueSequential techniqueSpinal anaesthesiasubarachnoid block

Identifiers

PMID42145407
PMCPMC13177149

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.