Comparative evaluation of non-surgical and surgical treatment modalities for oral cancer.

Akhil Trivedi, J K Savita, Mayuri Jain, Devashree Shukla, Monika Tanwar, Mona Janak Shah, Tanvi Hirani

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In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Akhil TrivediDepartment of Dentistry, Government Medical College, Orai, Jalaun, Uttar Pradesh, India.

J K SavitaDepartment of Oral Pathology & Microbiology, Rajarajeswari Dental College & Hospital, Bangalore, India.

Mayuri JainDepartment of Oral Medicine and Radiology, Maharana Pratap College of Dentistry and Research Centre, Gwalior, Madhya Pradesh, India.

Devashree ShuklaDepartment of Dentistry, LN Medical College and J K Hospital, Kolar Road, Bhopal, Madhya Pradesh, India.

Monika TanwarDepartment of Oral and Maxillofacial Surgery, SGT University, Gurgaon, Haryana, India.

Mona Janak ShahDepartment of Oral Medicine & Radiology, Dharmsinh Desai University, Nadiad, Gujarat, India.

Tanvi HiraniDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer treatment decisions between surgery and non-surgical approaches critically impact survival and quality of life outcomes worldwide. This retrospective cohort study compared surgical treatment (n=98) versus definitive chemoradiotherapy (n=82) in 180 patients with oral squamous cell carcinoma diagnosed 2017-2021. The surgical group demonstrated superior 3-year overall survival (68.4% vs 52.4%, p=0.018) and disease-free survival (61.2% vs 44.0%, p=0.012). Locoregional recurrence was significantly lower with surgery (24.5% vs 39.0%, p=0.032), while distant metastasis rates remained comparable (14.3% vs 17.1%, p=0.608). Surgery provides superior oncologic outcomes for early, localised oral squamous cell carcinoma, while non-surgical options remain valuable for inoperable cases or significant comorbidities.

Indexed as

chemoradiotherapyOral canceroral squamous cell carcinoma (OSCC)surgical treatmentsurvival outcomestreatment effectiveness

Identifiers

PMID42145375

DOI10.6026/973206300221374

PMCPMC13177047

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.