Evidence map›Paper›PMID 42145361›Full record

ArticleBioinformation2026

Evaluating the most effective combination of needle gauge with TENS, EMLA or topical spray for minimal pain during pediatric local anaesthesia: A randomized clinical trial.

Sai Vaishnavi Alahari, Sampath Reddy Cheruku, Ambika K Nandini, Ziauddin Mohammad, Silla Swarna Swathi, Anusha Reddy Gollampalli

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sai Vaishnavi AlahariDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Sampath Reddy CherukuDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Ambika K NandiniDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Ziauddin MohammadDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Silla Swarna SwathiDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Anusha Reddy GollampalliDepartment of Pedodontics and Preventive Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain and anxiety during dental local anesthesia injections remain a significant challenge in pediatric dentistry, often leading to fear, poor cooperation, and negative treatment experiences in children. Therefore, it is of interest to compare the effectiveness of transcutaneous electric nerve stimulation (TENS), EMLA cream as well as conventional lignocaine topical spray, in conjunction with needles that were 25- gauge and 30-gauge for relieving anxiety and pain in children's during dental local anesthesia administration. Around 180 children ranging from 8 to 12 years old were randomly divided into six groups of equal size (n=30 for each group). The pain was evaluated via FLACC and VAS while anxiety was assessed with the Venham's Anxiety Scale along with pulse rate. The least anxiety and pain outcomes were found for the TENS + 30 gauge group, which demonstrated the longest-lasting pulse response and also the lowest score on FLACC and VAS (p less than 0.05). EMLA 30 gauge also showed less pain when compared to sprays applied to the skin, but were lower than TENS. Thus, we show using TENS that has a needle of a fine gauge as a safe, effective aid to improve the comfort of local anesthetic administration.

Indexed as

dental anxietyeutectic mixture of local anesthetics (EMLA)local anesthesiaPediatric dentistrytranscutaneous electric nerve stimulation (TENS)

Identifiers

PMID42145361
PMCPMC13177131

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