ArticleBioinformation2026
Blood - brain barrier breakdown and neurovascular unit failure in the progression of Alzheimer's disease.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder traditionally defined by amyloid-β deposition and tau pathology. Recent research highlights the role of blood-brain barrier (BBB) breakdown and neurovascular unit (NVU) dysfunction in disease initiation and progression. These factors contribute to neuroinflammation, cerebral hypoperfusion and impaired waste clearance. Despite this, the relationship between BBB integrity, NVU function and cognitive decline in AD remains inadequately understood. Data shows that blood-brain barrier disruption and neurovascular unit dysfunction are critical predictors of cognitive decline in Alzheimer's disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.