Evidence map›Paper›PMID 42145213›Full record

ArticleEpidemiology and infection2026

Investigation of an ongoing cluster of tuberculosis (TB) associated with prisons, England.

Lucy Findlater, Mailis Maes, Nathan Post, Amith Philip, Lauren Ahyow, Chantal Edge, Martin Dedicoat, Tracey Langham, Suzi Coles, Esther Robinson

Abstract read
In one paragraph

Article in Epidemiology and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucy FindlaterUK Field Epidemiology Training Programme, https://ror.org/00vbvha87UK Health Security Agency, UK.ORCID https://orcid.org/0000-0003-1736-7661
Mailis MaesTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.
Nathan PostHealth Protection in the Regions, https://ror.org/00vbvha87UK Health Security Agency, UK.
Amith PhilipHealth Protection in the Regions, https://ror.org/00vbvha87UK Health Security Agency, UK.
Lauren AhyowTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.
Chantal EdgeHealth Equity and Inclusion Health Division, https://ror.org/00vbvha87UK Health Security Agency, UK.
Martin DedicoatTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.
Tracey LanghamTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.
Suzi ColesTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.
Esther RobinsonTuberculosis Unit, https://ror.org/00vbvha87UK Health Security Agency, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prisons are high-risk environments for the spread of tuberculosis (TB). We investigated an ongoing prison-associated TB cluster to identify common exposures. We defined cases as residents in England with laboratory-confirmed TB belonging to the genetic cluster. We extracted records from the National TB Surveillance System, linked to prison operational data, and conducted descriptive analysis of demographic, clinical, and phylogenetic data. Years were masked for anonymity. Over six years, 12 individuals were identified, predominantly male (83%) and median age 34 years, in London, East Midlands, and East of England. Prison history was noted for 7/12 (58%) at 13 prisons. Everyone without prison history completed treatment, but 2/7 with prison history were lost to follow-up and 5/7 were still in treatment or outcome not evaluated. We identified frequent prison transfers and concurrent stays of four individuals at Prison B, and two at Prison G. Phylogenetic analysis indicated distinct sub-clusters with and without prison history, suggesting expansion of the cluster from community into prisons. Prisons continue to play a role in TB in England. Factors such as frequency of transfers could hinder treatment completion and control of transmission. Combining phylogenetic, epidemiological, and prison operational data facilitated investigation of transmission pathways.

Indexed as

Mycobacterium tuberculosisPrisonsTuberculosisAdultCluster AnalysisEnglandFemaleHumansMaleMiddle AgedPhylogenyPrisonersYoung AdultCommunicable Disease ControlDisease OutbreaksPrisonsTuberculosisWhole Genome Sequencing

Identifiers

PMID42145213
PMCPMC13312352

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.