Evidence map›Paper›PMID 42145140›Full record

ArticleMolecular plant pathology2026

Identification of Genes Involved in Resistance to Flavescence Dorée Disease of Grapevine: A Model Study Using Arabidopsis thaliana.

Marika Rossi, Luciana Galetto, Simona Abbà, Nicola Bodino, Cristina Marzachì, Sabrina Palmano

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In one paragraph

Article in Molecular plant pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Marika RossiInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.
Luciana GalettoInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.ORCID 0000-0001-6637-0678
Simona AbbàInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.
Nicola BodinoInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.
Cristina MarzachìInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.
Sabrina PalmanoInstitute for Sustainable Plant Protection - National Research Council of Italy, IPSP-CNR, Torino, Italy.ORCID 0000-0002-7729-6044

Funding

European Union NextGenerationEU 2022FW39MTRegione Piemonte J65E25000080007
6 · The paper itself

Abstract

Flavescence dorée (FD), caused by FD phytoplasma (FDp) and transmitted by the leafhopper Scaphoideus titanus, is a quarantine disease that seriously threatens viticulture across Europe. Research on resistance or tolerance to FDp in grapevine is limited by the perennial nature of the host, high cultivar variability and the univoltine life cycle of the insect vector. To overcome these constraints, we employed Arabidopsis thaliana as a model host to identify genes conferring resistance to FDp. RNA sequencing (RNA-seq) was first used to identify genes deregulated in A. thaliana during infection by either the woody host pathogen FDp or the herbaceous host pathogen Chrysanthemum yellows phytoplasma (CYp). A subset of these genes was then validated by monitoring their expression in the FDp-A. thaliana pathosystem at various time points during infection. Five genes were consistently deregulated upon infection, and functional analysis of the corresponding mutants revealed two lines with significantly reduced susceptibility to FDp compared with the wild type. The double mutant combining these two genes exhibited a similar phenotype, suggesting functional convergence. Electrical penetration graph (EPG) analysis indicated that this resistance is independent of vector feeding behaviour, pointing to a genetically determined defence mechanism rather than antixenosis. These findings uncover novel components of plant defence against phytoplasma infection and establish A. thaliana as a valuable system for dissecting the molecular basis of tolerance to FDp. We discussed how the genes we identified represent promising targets for developing sustainable, phytoplasma-resistant grapevine varieties.

Indexed as

ArabidopsisDisease ResistanceGenes, PlantPhytoplasma DiseasePlant DiseasesVitisAnimalsGene Expression Regulation, PlantMutationPhytoplasmadifferential gene expressionelectrical penetration graph EPGphytoplasmareverse geneticsRNAseqsusceptibility

Identifiers

PMID42145140
PMCPMC13181333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.