Evidence map›Paper›PMID 42145107›Full record

ArticleAnnals of medicine2026

Neoadjuvant immunochemotherapy and postoperative acute hypoxemic respiratory failure in thoracic surgery: a multicentre cohort study.

Shenglan Tan, Yang Sun, Yixin Peng, Yongkang Liu, Xue He, Hengxing Liang

Abstract readMulticenter Study
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shenglan TanDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P.R China.
Yang SunDepartment of Thoracic Surgery, Guilin Hospital of the Second Xiangya Hospital, Central South University, Guilin, Guangxi, P.R China.
Yixin PengDepartment of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P.R China.
Yongkang LiuDepartment of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P.R China.
Xue HeDepartment of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, P.R China.ORCID 0000-0003-1641-6134
Hengxing LiangDepartment of Thoracic Surgery, Guilin Hospital of the Second Xiangya Hospital, Central South University, Guilin, Guangxi, P.R China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWhile immune checkpoint inhibitors (ICIs) continue to transform the neoadjuvant treatment, its association with postoperative acute hypoxemic respiratory failure (AHRF) remains unexplored. This study aims to assess the association between neoadjuvant immunochemotherapy (nICT) and postoperative AHRF risk following thoracic tumour surgeries and identify the risk subgroups.

methodsThis retrospective two-centre cohort study included 327 patients receiving nICT (

resultsThe nICT group demonstrated significantly higher postoperative AHRF incidence than the nCT group (19.8% vs. 8.1%,

conclusionsnICT was associated with increased postoperative AHRF risk in thoracic surgical patients, necessitating rigorous perioperative monitoring.

Indexed as

HypoxiaImmune Checkpoint InhibitorsImmunotherapyLung NeoplasmsNeoadjuvant TherapyPostoperative ComplicationsRespiratory InsufficiencyThoracic Surgical ProceduresAgedCarcinoma, Non-Small-Cell LungFemaleHumansMaleMiddle AgedRetrospective StudiesImmune Checkpoint Inhibitorsacute hypoxemic respiratory failureNeoadjuvant chemotherapyneoadjuvant immunochemotherapynon-small cell lung cancerthoracic surgery

Identifiers

PMID42145107
PMCPMC13185069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.