ArticleAnnals of medicine2026
Neoadjuvant immunochemotherapy and postoperative acute hypoxemic respiratory failure in thoracic surgery: a multicentre cohort study.
Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Neoadjuvant immunochemotherapy and postoperative acute hypoxemic respiratory failure in thoracic surgery: a multicentre cohort study.Annals of medicine · 2026Article
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6 authors.
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Abstract
objectivesWhile immune checkpoint inhibitors (ICIs) continue to transform the neoadjuvant treatment, its association with postoperative acute hypoxemic respiratory failure (AHRF) remains unexplored. This study aims to assess the association between neoadjuvant immunochemotherapy (nICT) and postoperative AHRF risk following thoracic tumour surgeries and identify the risk subgroups.
methodsThis retrospective two-centre cohort study included 327 patients receiving nICT (
resultsThe nICT group demonstrated significantly higher postoperative AHRF incidence than the nCT group (19.8% vs. 8.1%,
conclusionsnICT was associated with increased postoperative AHRF risk in thoracic surgical patients, necessitating rigorous perioperative monitoring.
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