Evidence map›Paper›PMID 42145037›Full record

ReviewJournal of leukocyte biology2026

Tissue adaptation of eosinophils.

Clotilde Marie Lacroix, Kalyani Kulkarni, Nicola Laura Diny

Abstract readReview
In one paragraph

Review in Journal of leukocyte biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Clotilde Marie LacroixInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Venusberg-Campus 1, Bonn 53127, Germany.ORCID 0009-0001-8742-6375
Kalyani KulkarniInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Venusberg-Campus 1, Bonn 53127, Germany.ORCID 0009-0007-7724-5179
Nicola Laura DinyInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Venusberg-Campus 1, Bonn 53127, Germany.ORCID 0000-0002-9145-5216

Funding

Deutsche ForschungsgemeinschaftGerman Research Foundation 432325352German Research Foundation SFB 1454University of BonnWellcome Trust 220497/Z/20/Z
6 · The paper itself

Abstract

Eosinophils are increasingly recognized as tissue-resident immune cells that take on diverse functions. Recent studies have shed light on the pathways that result in tissue-specific eosinophil phenotypes. In this review, we discuss the process of tissue adaptation covering the local environmental cues that trigger adaptation, the transcriptional reprograming that occurs in response, and the phenotypic, metabolic, and functional adaptation that leads to varied eosinophil populations across the body. We further examine the relative impact of trained immunity and systemic factors versus local signals on eosinophil plasticity in the context of homeostasis and inflammation.

Indexed as

Adaptation, PhysiologicalEosinophilsTrained ImmunityAnimalsHomeostasisHumansOrgan Specificityeosinophilsmetabolismmicroenvironmenttissue adaptationtranscriptional regulation

Identifiers

PMID42145037
PMCPMC13245579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.