Evidence map›Paper›PMID 42144970›Full record

ArticleJournal of neurochemistry2026

N,N-Dimethyltryptamine (DMT) Acutely Exposed to Mouse Ventral Tegmental Area I

Jannik Nicklas Eliasen, Amir Rezagholizadeh, Helene Påbøl Jacobsen, Kristi A Kohlmeier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jannik Nicklas EliasenDrug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Amir RezagholizadehDrug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Helene Påbøl JacobsenDrug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kristi A KohlmeierDrug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-0183-3816

Funding

Sino-Danish Center 118930_2020
6 · The paper itself

Abstract

Depression and substance use disorder (SUD) affect millions globally and unfortunately, while established treatments exist, they are not always adequate. Psychedelics have emerged as a promising avenue for development of more effective pharmacological interventions. Dimethyltryptamine (DMT), a classic psychedelic, has shown anti-depressive and anti-addictive properties in preclinical studies, observational evaluations, and limited controlled trials; however, the exact mechanism(s) of action(s) are still unknown. In the present ex vivo study, we provide the first evaluation of the electrophysiological effects of acute DMT exposure at two concentrations in male and female I

Indexed as

Action PotentialsHallucinogensNeuronsN,N-DimethyltryptamineSex CharacteristicsVentral Tegmental AreaAnimalsDose-Response Relationship, DrugFemaleMaleMiceMice, Inbred C57BLHallucinogensN,N-Dimethyltryptaminedimethyltryptamineelectrophysiologypsychedelicsex‐differences

Identifiers

PMID42144970
PMCPMC13181311

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.