SynthesisGerodontology2026
Adverse Oral Health in Older Adults With Head and Neck Cancer (And Oral Potentially Malignant Disorders): A Systematic Review.
Synthesis in Gerodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Staging in Gerodontology: A Framework.Gerodontology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis systematic review evaluated oral health, including oral health-related quality of life (OHRQoL), in older adults with head and neck cancer (HANC) or oral potentially malignant disorders (OPMDs). The PICO/PECO focus question for this study was: 'What is the incidence/prevalence of adverse oral health (O) among people aged 60 years or older (P) who have been diagnosed with HANC or an OPMD (E), relative to people aged 60 years or older who have not been diagnosed with HANC or an OPMD, or younger people aged less than 60 years who have been diagnosed with HANC or an OPMD (C)?'
methodsA comprehensive literature search was performed across PubMed, OVID Medline, CENTRAL and Embase, guided by the PICO/PECO framework. Publications from 1960 up to April 2025 were considered, yielding 1070 records for initial screening.
resultsA total of eight studies were included for analysis. A narrative review only was presented. Findings from the included studies demonstrated conflicting results. Two cross-sectional studies demonstrated better post-treatment OHRQoL across some domains for older patients with HANC than younger patients; however, this was contradicted by data from two prospective cohort studies which showed no differences in post-treatment OHRQoL between older and younger patients with a history of HANC. Findings from a different prospective cohort study demonstrated a linear relationship between HANC patients' age and the incidence of post-radiotherapy moderate-severe xerostomia. There were no data on oral health consequences among older adults with OPMDs.
conclusionsThis systematic review revealed inconclusive findings on the impact of HANC and OPMD on oral health in older adults. PROSPERO REGISTRATION: CRD420251003419.
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Registered trials
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