Evidence map›Paper›PMID 42144881›Full record

SynthesisGerodontology2026

Functional Outcomes of Prosthetic Rehabilitation in Older Adults With Tooth Loss: A Systematic Review and Meta-Analysis.

Pedro Molinero-Mourelle, Azize Bell, Najla Chebib, Manabu Kanazawa, Frauke Müller, Annika Neri, Takahiro Ono, Masako Shiramizu, Sayaka Tada

Abstract readSystematic ReviewMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Gerodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pedro Molinero-MourelleDepartment of Conservative Dentistry and Prosthodontics, Faculty of Dentistry, Complutense University of Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0001-5493-0295
Azize BellDepartment of Prosthetic Dentistry and Material Science, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID https://orcid.org/0009-0005-7926-0765
Najla ChebibDivision of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-4094-6955
Manabu KanazawaDepartment of Gerodontology and Oral Rehabilitation, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2587-5455
Frauke MüllerDivision of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0003-3981-0134
Annika NeriDepartment of Gerodontology and Oral Rehabilitation, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0003-7308-1454
Takahiro OnoDepartment of Geriatric Dentistry, Osaka Dental University, Osaka, Japan.ORCID https://orcid.org/0000-0003-2087-4971
Masako ShiramizuDepartment of Dental Hygiene, Kyoto Koka University Junior College, Kyoto, Japan.ORCID https://orcid.org/0000-0003-1374-0350
Sayaka TadaFaculty of Dentistry, National University of Singapore, Singapore.ORCID https://orcid.org/0000-0002-9952-4239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the effect of prosthodontic treatment and management on oral function and oral-health-related patient reported outcome measures (PROMs) in older adults with tooth loss.

methodsA systematic search of four databases identified clinical studies (≥ 10 participants) reporting functional or PROM outcomes in partially or fully edentulous adults ≥ 65 years rehabilitated with dental prostheses for ≥ 6 months. Pooled standardized mean differences in pre-post changes were estimated by prosthesis type and follow-up using random-effects models (REML), with heterogeneity assessed by Cochran's Q and I

resultsFrom an initial 7654 studies, 24 were included in this review, covering 1711 individuals. Fourteen studies assessed masticatory performance (MP), masticatory ability (MA), and maximum bite force (MBF). Complete dentures (CDs) showed modest functional improvement, while implant overdentures (IODs) consistently produced higher MP and MBF with significant long-term improvements. Eighteen studies evaluated OHRQoL using OHIP variants, OIDP, and modified GOHAI-11. IODs and fixed full-arch prostheses showed the greatest improvements, while CDs and removable partial dentures were associated with smaller but positive changes. Subjective MA improved over 6-12 months post insertion in regardless groups, with high heterogeneity. OHRQoL showed short-term benefits of implant-supported prostheses, particularly for OHIP-20, while OHIP-14 results were inconsistent over time, indicating more reliable functional and patient-reported outcomes with dental implants.

conclusionsTooth loss leads to functional and psycho-social limitations, and although restorative measures can alleviate these shortcomings, they require ongoing maintenance, highlighting the complexity of care in this vulnerable older population.

trial registrationPROSPERO International prospective register of systematic reviews (CRD420251077683).

Indexed as

Tooth LossAgedBite ForceDental Prosthesis, Implant-SupportedDenture, CompleteHumansMasticationPatient Reported Outcome MeasuresTreatment Outcomebite forcechewingdental prosthesismasticatory performanceOHRQoLpatient‐reported outcomestooth loss

Identifiers

PMID42144881
PMCPMC13498934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.