Evidence map›Paper›PMID 42144866›Full record

Observational studyHIV medicine2026

Hodgkin and non-Hodgkin lymphomas in the post-antiretroviral therapy era according to HIV virological suppression.

Teresa Aldámiz-Echevarria, Francisco Tejerina, Chiara Fanciulli, Cristina Diez, Leire Perez, José Maria Bellón, Nuria Espinosa, Santiago Moreno Guillén, Maria Del Mar Arcos-Rueda, Marta Montero-Alonso and 20 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in HIV medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Teresa Aldámiz-EchevarriaServicio de Microbiología Clínica y Enfermedades Infecciosas, Gregorio Marañón General University Hospital, Madrid, Spain.
Francisco TejerinaServicio de Microbiología Clínica y Enfermedades Infecciosas, Gregorio Marañón General University Hospital, Madrid, Spain.
Chiara FanciulliServicio de Microbiología Clínica y Enfermedades Infecciosas, Gregorio Marañón General University Hospital, Madrid, Spain.
Cristina DiezServicio de Microbiología Clínica y Enfermedades Infecciosas, Gregorio Marañón General University Hospital, Madrid, Spain.
Leire PerezServicio de Microbiología Clínica y Enfermedades Infecciosas, Gregorio Marañón General University Hospital, Madrid, Spain.
José Maria BellónInstituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.
Nuria EspinosaUnidad clínica de Enfermedades Infecciosas, microbiología y parasitologías (UCEIMP), Hospital Universitario Virgen del Roci), Sevilla, Spain.
Santiago Moreno GuillénHead Department of Infectious Diseases, Jefe de Servicio de Enfermedades Infecciosas, Madrid, Spain.
Maria Del Mar Arcos-RuedaHIV Unit. Internal Medicine Department, Hospital Universitario La Paz-Carlos III, IdiPAZ, Madrid, Spain.ORCID https://orcid.org/0000-0002-9961-5544
Marta Montero-AlonsoUnidad de Enfermedades Infecciosas Hospital Universitario y Politécnico La Fe, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.ORCID https://orcid.org/0000-0002-3432-5394
Lucio García-FraileCIBERINFEC, ISCIII - CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.ORCID https://orcid.org/0000-0002-2512-6107
Victor AsensiHIV Unit. Internal Medicine Service Hospital Universitario Central de Asturias (HUCA), Oviedo University School of Medicine, Investigator, Microbiology and Infectious Diseases Group, ISPA-FINBA, Oviedo, Spain.ORCID https://orcid.org/0000-0003-4211-456X
Marian Fernández LópezUnidad de VIH-UNITS, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
Diana Corona-MataServicio de Enfermedades Infecciosas, Hospital Universitario Reina Sofía, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba (UCO), Córdoba, Spain.
Alfonso Cabello-ÚbedaDivisión de Enfermedades Infecciosas, Hospital Universitario Fundación Jiménez Díaz. Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain.ORCID https://orcid.org/0000-0001-8429-8358
Meritxell Gavaldà MansoServicio de Medicina Interna, Hospital Universitari Son Espases, Mallorca, Spain.ORCID https://orcid.org/0000-0003-4663-8117
Jose Antonio IribarrenServicio de Enfermedades Infecciosas, Hospital Universitario Donostia. IIS BioGipuzkoa. Departamento de Medicina; EHU-Universidad del País Vasco, San Sebastián, Spain.
Laura Pérez-MartínezFundación Rioja Salud CIBIR, Logroño, Spain.
María Remedios Alemán VallsHospital Universitario de Canarias, San Cristóbal de La Laguna, Spain.
Irene Portilla-TamaritDepartment of Health Psychology, University of Alicante, Alicante, Spain.ORCID https://orcid.org/0000-0002-2187-8731
Joaquim PeraireHospital Universitari Joan XXIII de Tarragona, Tarragona, Spain.
Inés Suárez-GarcíaServicio de Medicina Interna, Hospital Universitario Infanta Sofía, FIIB HUIS HHEN, San Sebastián de los Reyes, Spain.ORCID https://orcid.org/0000-0002-7016-716X
Mar MasiáUnidad de Enfermedades Infecciosas, Hospital General Universitario De Elche & Universidad Miguel Hernández, Alicante. CIBERINFEC, Carlos III Health Institute, Madrid, Spain.
María José Núñez OrantosUnidad de Infecciosas de Medicina Interna del hospital Clínico San Carlos de Madrid. CIBERINFEC con código CB 21/1300126, Carlos III Health Institute, Madrid, Spain.ORCID https://orcid.org/0000-0002-6715-590X
Ángela Gutiérrez LiarteEspecialista en Medicina Interna/E. Infecciosas, Hospital Universitario de La Princesa, Madrid, Spain.ORCID https://orcid.org/0000-0003-0217-5122
Arkaitz ImazHIV and STI Unit, Department of Infectious Diseases, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, Spain.
Cristina Hernández GutiérrezServicio de Medicina Interna, Hospital Universitario Príncipe de Asturias Alcalá de Henares. Madrid. Conflictos de interés: I report personal fees from Gilead Sciences, ViiV, MSD and Janssen for developing educational presentations, Alcalá de Henares, Spain.
Maria Tasias PitarchUnidad de Enfermedades Infecciosas, Valencia, Spain.
Marta RavaCoRIS coordination unit, Carlos III Health Institute and CIBERINFEC, Carlos III Health Institute, Madrid, Spain.
CoRIS Cohort

Funding

CIBER-Consorcio Centro de Investigación Biomédica en Red CB21/13/00091Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea-NextGenerationEU
6 · The paper itself

Abstract

objectivesLymphomas remain among the most frequent HIV-associated malignancies, with risk persisting despite effective virological control. This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non-Hodgkin [NHL]) in people living with HIV (PLWH), according to virological suppression at diagnosis and assesses lymphoma-related mortality at 1 year and overall survival at 5 years.

methodsWe conducted a multicentre retrospective study including PLWH from the Spanish CoRIS cohort, who were diagnosed with lymphoma between 2004 and 2022 and had HIV viral load data at diagnosis. Virological suppression was defined as HIV-1 RNA <100 copies/mL within the 6 months prior to and 1 month following lymphoma diagnosis.

resultsAmong 18 573 PLWH included in CoRIS, 291 developed lymphoma, with virological data available for 245 individuals, of whom 49 (20%) had virological suppression. People with detectable HIV viral load had lower CD4 counts (median 180 cells/mm

conclusionsIn PLWH diagnosed with lymphoma, prognosis is independent of HIV virological status at diagnosis. These findings support that lymphoma management in PLWH should be guided by standard oncological criteria, alongside antiretroviral therapy, regardless of HIV viral suppression status.

Indexed as

HIV InfectionsHodgkin DiseaseLymphoma, Non-HodgkinAdultCD4 Lymphocyte CountFemaleHumansLymphoma, AIDS-RelatedMaleMiddle AgedPrognosisRetrospective StudiesSpainViral LoadHIV‐associated malignancieslymphomasurvivalvirological suppression

Identifiers

PMID42144866
PMCPMC13432415

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.