ArticleJournal of paediatrics and child health2026
Relationships of Early Parenteral Nutrition and Human Milk Fortification on the Growth of Neonates With Birth Weights Between 1500 and 1750 g.
Article in Journal of paediatrics and child health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionLow-birthweight infants have high nutrient requirements; however, early parenteral nutrition (EPN) and human milk fortification (HF) are provided in very low-birthweight infants. We changed the indications for EPN and HF from very low birth weight to birth weight < 1750 g in our hospital in April 2019.
aimThis study aimed to assess the growth and neurodevelopmental relationships in infants with birth weights between 1500 and 1750 g, with or without EPN and HF.
methodsA retrospective cohort study was conducted using the medical records of infants with birth weights between 1500 and 1750 g from April 2016 to March 2022, who were divided into two groups: before and after the change in indication.
resultsEPN and HF promoted head circumference expansion during hospitalization. However, no relationships on growth were noted after hospital discharge. Furthermore, no difference in the incidence of complications was observed among the preterm infants, and relatively few adverse events associated with EPN and HF led to safe nutritional management.
conclusionFor infants with birth weights between 1500 and 1750 g, EPN and HF may improve short-term growth, but may not have an impact in the long term.
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