Evidence map›Paper›PMID 42144726›Full record

ReviewClinical endocrinology2026

What Endocrinologists Should Know About Iodine: Population Deficiency, Individual Excess and Misinformation in the United Kingdom.

Peter N Taylor, Malcolm Prentice, Sarah Bath, Emilie Combet, Nadia Schoenmakers, Vicki E Smith, Fraser W Gibb, Nicola Zammitt, Onyebuchi Okosieme, Kristien Boelaert and 2 more

Abstract readReview
In one paragraph

Review in Clinical endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peter N TaylorDepartment of Immunology and Immunotherapy, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Malcolm PrenticeNuffield Health, Epsom, UK.
Sarah BathDiscipline of Nutrition, Exercise, Chronobiology and Sleep, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Emilie CombetSchool of Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.
Nadia SchoenmakersSchool of Medical Sciences, Metabolism & Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Vicki E SmithSchool of Medical Sciences, Metabolism & Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Fraser W GibbUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-5576-6463
Nicola ZammittEdinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK.
Onyebuchi OkosiemeThyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK.ORCID https://orcid.org/0000-0003-2221-992X
Kristien BoelaertDepartment of Applied Health Research, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-6435-177X
John LazarusThyroid Research Group, Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK.
Mark VanderpumpOneWelbeck Endocrine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iodine deficiency, once considered eliminated in the United Kingdom, has re-emerged, particularly among women of reproductive age, in whom requirements are increased during pregnancy and lactation. The declining consumption of dairy and white fish, the emerging use of unfortified plant-based milk alternatives, and the absence of a national iodisation policy have contributed to a return of mild to moderate iodine deficiency. Vegans and individuals avoiding dairy are at particular risk. Simultaneously, social-media-driven wellness trends promote 'thyroid detoxes' or 'iodine resets' and kelp-based supplements that deliver supraphysiological iodine doses far exceeding recommended intake. Endocrinologists now face a dual challenge: widespread under-recognition of population iodine insufficiency and a growing minority of patients presenting with iodine-induced thyroid dysfunction. This review summarises current UK iodine status, the physiological and clinical relevance of iodine to thyroid and neurodevelopmental health, modern dietary risk factors and the clinical approach to those influenced by online misinformation. Routine dietary counselling and public health fortification represent cost-effective interventions to prevent both extremes. Population-based solutions would correct iodine status efficiently and align the UK with other high-income countries.

Indexed as

IodineDietary SupplementsEndocrinologyFemaleHumansPregnancyUnited KingdomIodineIodine deficiencykelpmisinformationpregnancypublic health nutritionthyroidUnited Kingdom

Identifiers

PMID42144726
PMCPMC13629602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.