Observational studyContact dermatitis2026
Patch Testing in Chronic Hand Eczema: A Multicentre Study in Portugal.
Observational study in Contact dermatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Patch Testing in Chronic Hand Eczema: A Multicentre Study in Portugal.Contact dermatitis · 2026Observational
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic hand eczema (CHE) is a common dermatitis with morphological and aetiological heterogeneity. Allergic contact dermatitis (ACD) is a major aetiology, and patch testing (PT) is essential to characterize CHE and guide its treatment and prevention.
objectivesDetermine the prevalence of ACD in CHE patients, describe relevant allergens, and identify differences in atopic and occupational settings.
methodsWe conducted a multicentric retrospective observational study, based on PT results of CHE patients evaluated between 2021 and 2023, in Portuguese dermatology departments, comparing atopic dermatitis and non-atopic and occupational and non-occupational groups.
resultsAmong 1267 patients (391 males/876 females) with CHE, representing 43% of all patients tested, 57% had at least one positive PT reaction, 41% of which were currently relevant. The most common allergens included metals, preservatives, fragrances, rubber constituents and 2-hydroxyethyl methacrylate. The occupational group revealed higher relevance rates for metals and benzisothiazolinone, whereas in the atopic dermatitis group, methylisothiazolinone and Myroxylon pereirae were considered more frequently relevant.
conclusionsCHE patients present a high sensitization rate and ACD is a main aetiology. Methylisothiazolinone and 2-hydroxyethyl methacrylate are confirmed as emergent allergens. The higher relevance rate of metals and benzisothiazolinone in the occupational group reinforces the importance of PT in the occupational setting.
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