Evidence map›Paper›PMID 42144590›Full record

Trial reportBMC neurology2026

Effects of lower limb exoskeleton robot-assisted rehabilitation on motor function, activities of daily living, and electromyography in hemiplegic stroke: a randomized controlled trial.

Congzhi Tang, Yun Zhang, Ting Zhou, Ruian Yin, Lixia Zhang, Caili Ren, Zunke Gong, Yanyun Wu, Yuxian Chen, Yonggang Zhu and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Congzhi TangRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Yun ZhangRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Ting ZhouRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Ruian YinRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Lixia ZhangDepartment of Rehabilitation Medicine, Jiangsu Province Official Hospital, Nanjing, Jiangsu, China.
Caili RenDepartment of Rehabilitation Medicine, Wuxi Central Rehabilitation Hospital, Wuxi, Jiangsu, China.
Zunke GongDepartment of Rehabilitation Medicine, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.
Yanyun WuDepartment of Rehabilitation Medicine, The Fifth People's Hospital of Huaian, Huaian, Jiangsu, China.
Yuxian ChenDepartment of Rehabilitation Medicine, The Fifth People's Hospital of Huaian, Huaian, Jiangsu, China.
Yonggang ZhuDepartment of Rehabilitation Medicine, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China.
Pengfei SongRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Wenli ChenRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China. banlilizhi@163.com.
Hongxing WangRehabilitation Medicine Department, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China. 101012648@seu.edu.cn.

Funding

Horizontal Project of Hangzhou Chengtian Technology Development Co., LTD fund (H2021010103)Jiangsu Provincial Medical Key Discipline Cultivation Unit (JSDW202202, ZDXYS202210)Key Project of Jiangsu Province's Key Research and Development Program (No.BE2023023-4)National Key Research and Development Program of China (No. SQ2025YFE0202777)
6 · The paper itself

Abstract

backgroundPost-stroke lower limb dysfunction affects the quality of life. Previous studies have confirmed that lower limb exoskeleton robots can improve the walking ability of stroke patients. This study aims to explore the impact of the UGO220 exoskeleton rehabilitation robot on the motor function and daily living ability of chronic stroke patients and to observe changes in lower limb muscle activity by surface electromyography before and after treatment.

methodsSixty stroke patients with hemiplegia were randomly divided into a conventional (CT, n = 30) group or a robot (RT, n = 30) group. Patients in both groups received 60 min of routine physical therapy and occupational therapy. The robot group received 30 min of lower limb exoskeleton robot-assisted gait training per day, whereas the conventional group received 30 min of physical therapist-assisted gait training per day, six days a week, for three consecutive weeks. The primary outcome was evaluated by Fugl-Meyer assessment-lower extremities (FMA-LE), and the secondary outcomes included the modified Barthel index (MBI) score, Berg balance scale (BBS), and lower extremity muscle surface electromyography (sEMG) of the rectus femoris, biceps femoris, anterior tibialis and medial gastrocnemius muscles, including the integrated EMG (iEMG) and root-mean-square (RMS) values.

resultsThe robot group had significantly greater improvements in FMA-LE and MBI compared to the conventional group. The electromyography results indicated that in terms of the activation of the anterior tibial muscle, the robot group performed better than the traditional group.

conclusionsThe UGO220 exoskeleton robot training is superior to conventional training in improving Activities of daily living and lower limb motor function. Moreover, it can better promote the improvement of the ankle dorsiflexion function.

trial registrationClinicalTrials.gov (ChiCTR2500096316)(2025-01-21).

Indexed as

Activities of Daily LivingExoskeleton DeviceHemiplegiaLower ExtremityRoboticsStrokeStroke RehabilitationAgedElectromyographyFemaleHumansMaleMiddle AgedTreatment OutcomeActivities of daily livingElectromyographyLower limb exoskeleton robot-assisted rehabilitationMotor functionStroke

Identifiers

PMID42144590
PMCPMC13348571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.