ArticleCell and tissue research2026
The subcellular distribution of methionine sulfoxide reductase A in mouse and human tissues.
Article in Cell and tissue research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among all known repair enzymes, methionine sulfoxide reductase A (MsrA) plays a key role in protecting against oxidative stress and its damaging effects. The enzyme is ubiquitously expressed in eukaryotic cells and different splice variants of the MsrA gene have been shown to permit the specific prevalence of the protein in different cell organelles. Here, we present novel insights in the intracellular localization of MsrA in selected samples from mouse and human tissue. Using immunocytochemical techniques at both the light and electron microscopic levels, we show incidence of MsrA in human oral mucosa cells, predominantly in the cell nucleus. In addition, the enzyme has been localized in mitochondria of mouse liver and kidney cells, in the cytoplasm of retina cells, and in the endoplasmic reticulum of glandular cells. Overall, the results indicate a correlation between the generation of reactive oxygen species (ROS) and the expression level of MsrA in subcellular compartments of the tissues examined.
Indexed as
Identifiers
42144479What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.