ArticleCommunications biology2026
Brain-wide information flow dynamics during novel visual processing in humans.
Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Brain-wide information flow dynamics during novel visual processing in humans.Communications biology · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The human brain's capacity for visual information processing is essential for higher-order cognitive functions, including facial recognition and spatial navigation. However, the millisecond-scale dynamics of cortico-subcortical information flow during novel visual stimulation remain unclear. To investigate this, we conducted intracranial electroencephalography (iEEG) recordings in 22 patients with refractory epilepsy as they underwent a picture-viewing task. Our findings showed region-specific modulations in high-frequency broadband (HFB, 60-160 Hz) activity across multiple brain regions, such as the dorsal and ventral visual streams, the limbic system, and higher-order cortical areas. Initial activation followed a hierarchical, back-to-front propagation pattern, starting from the primary visual areas, progressing through the ventral and dorsal streams, and ultimately engaging high-order cortical and limbic structures. Extensive top-down connectivity from higher-order cortex to limbic areas further revealed their role in novel visual processing, providing a high-resolution spatiotemporal map of visual information flow across brain regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.