ArticleJournal of echocardiography2026
Left atrial stiffness as a predictor of one-year mortality after transcatheter aortic valve replacement.
Article in Journal of echocardiography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn patients with aortic stenosis (AS), risk stratification for valve intervention is primarily based on valve severity, symptom burden, and left ventricular (LV) function. However, cardiac damage may extend beyond the LV to involve the left atrium (LA), which can contribute to adverse outcomes.
objectiveThis study aimed to evaluate the prognostic value of the left atrial stiffness (LAS) in predicting one-year all-cause mortality in patients undergoing transcatheter aortic valve replacement (TAVR).
methodWe conducted a retrospective study of patients with severe AS who underwent TAVR between 2010 and 2023 at a single tertiary center. LAS was calculated as the ratio of E/e' to LA reservoir strain (LASr) using speckle-tracking echocardiography. Univariable and multivariable Cox regression analyses were performed to identify predictors of one-year mortality. The optimal cutoff value of LAS was determined using receiver operating characteristic (ROC) curve analysis.
resultsAmong 260 patients, LAS was significantly higher in non-survivors than survivors (p < 0.001). In Cox regression analysis, LAS was strongly associated with one-year all-cause mortality (HR, 1.19; 95% CI, 1.11-1.27; p < 0.001) and remained an independent predictor after adjustment for multiple clinical and echocardiographic risk factors. ROC analysis identified an optimal cutoff of 1.69 (AUC 0.88; sensitivity 82%, specificity 80%), which was confirmed by bootstrap validation.
conclusionLAS independently predicts one-year mortality after TAVR and may serve as a valuable addition to established risk stratification models.
Indexed as
Identifiers
42143638What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.