Evidence map›Paper›PMID 42143582›Full record

ArticleSleep2026

Sleepiness and attention in sleep-clinic patients and their associations with apnea severity and treatment.

Allison Schwab, Brendan T Keenan, Nathan C Nowalk, Mathias Basner, Charles J Bae

Abstract read
In one paragraph

Article in Sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Allison SchwabDivision of Sleep Medicine/Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
Brendan T KeenanDivision of Sleep Medicine/Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-9070-847X
Nathan C NowalkDivision of Sleep Medicine/Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-8989-1131
Mathias BasnerUnit for Experimental Psychiatry, Division of Sleep and Chronobiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-8453-0812
Charles J BaeDivision of Sleep Medicine/Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.ORCID 0000-0003-2991-0617

Funding

RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
MicroRNAs as Biomarkers for Obstructive Sleep ApneaP01HL160471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Allan I Pack · 2023 to 2026
$11.9M
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation (MET12)F32HL182221 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI NOWALK, NATHAN · 2025 to 2025
$88k
NHLBI NIH HHS F32 HL182221NHLBI NIH HHS F32HL182221NHLBI NIH HHS P01 HL160471NHLBI NIH HHS T32 HL007605
6 · The paper itself

Abstract

STUDY

objectivesExcessive daytime sleepiness (EDS) is common in patients with sleep disorders, particularly obstructive sleep apnea (OSA). The Epworth Sleepiness Scale (ESS) and the Psychomotor Vigilance Test (PVT) are often used to measure sleepiness and attention/vigilance, respectively. However, whether these measures are correlated and their relationship to OSA severity/treatment remains understudied. This study examined these associations in a sleep center population.

methodsWe performed a prospective study of 165 participants (119 [72.1%] with diagnosed OSA) presenting to a sleep disorders clinic and completing ESS and PVT. Associations among ESS, PVT, OSA severity, and positive airway pressure (PAP) usage and efficacy were examined using Pearson's correlations, unadjusted and controlling for age, sex, and body mass index.

resultsResults showed no significant correlations between ESS and PVT measures of attention/vigilance. While higher ESS scores correlated with more severe apnea-hypopnea indices in patients with OSA, no association was found with OSA severity and PVT measures. Among participants using PAP, greater hours/night of usage was associated with lower ESS scores, but not with better PVT performance.

conclusionsWe found no association between sleepiness on the ESS and attention/vigilance on PVT among a sleep center population. ESS scores tracked more closely to OSA severity/treatment than PVT measures. The findings suggest that the sleepiness measured by the ESS and measures of sustained attention under monotonous conditions from the PVT capture distinct symptoms. While the ESS is commonly used, further research is needed to determine if the PVT should also be incorporated into clinical practice.

Indexed as

AttentionDisorders of Excessive SomnolenceSleep Apnea, ObstructiveSleepinessAdultContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedPolysomnographyProspective StudiesPsychomotor PerformanceSeverity of Illness IndexalertnessCPAPEpworth Sleepiness ScaleOSApsychomotor vigilance testPVTsleep apneasleepiness

Identifiers

PMID42143582
PMCPMC13357509

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.