Evidence map›Paper›PMID 42143352›Full record

ArticleBMC research notes2026

Prevalence and persistence of high-risk HPV genotypes in unvaccinated asymptomatic women: a six-year study in Peru.

Caddie Laberiano-Fernandez, Juana Del Valle-Mendoza, Miguel Angel Aguilar-Luis, Javier Arias-Stella, Denisse Champin, Graciela Risco de Domiguez, Francisco Perona-Fajardo, Fernando Jeancarlos Imán-Izquierdo, Luis J Del Valle, Wilmer Silva-Caso

Abstract read
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In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caddie Laberiano-Fernandez *Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Juana Del Valle-MendozaLaboratorio de Biomedicina, Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru. juana.delvalle@upc.pe.
Miguel Angel Aguilar-LuisLaboratorio de Biomedicina, Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Javier Arias-StellaInstitute of Pathology and Molecular Biology, Arias Stella, Lima, Peru.
Denisse ChampinFacultad de Ciencias de la Salud, Universidad Tecnológica del Perú, Lima, Peru.
Graciela Risco de DomiguezFacultad de Ciencias de la Salud, Universidad Tecnológica del Perú, Lima, Peru.
Francisco Perona-FajardoLaboratorio de Biomedicina, Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Fernando Jeancarlos Imán-IzquierdoUroginecology Service, Guillermo Almenara Irigoyen Hospital, Lima, Peru.
Luis J Del ValleBarcelona Research Center for Multiscale Science and Engineering, Departament d'Enginyeria Química, EE-BE, Universitat Politècnica de Catalunya (UPC), Barcelona, Spain.
Wilmer Silva-Caso *Laboratorio de Biomedicina, Centro de Investigación de la Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, Lima, Peru. wilmer.silva@upc.pe.

Funding

Universidad Peruana de Ciencias Aplicadas D-002-2023Universidad Peruana de Ciencias Aplicadas UPC-C-016-2024
6 · The paper itself

Abstract

objectiveThis study was to determine the frequency of HPV-hr and describe the distribution by categories (HPV16, HPV18, HPV-hr non16/18) among unvaccinated asymptomatic women in Peru over a 6-year period (2013-2018). In addition, the disease clearance rate is assessed in a percentage of cases.

resultsOf the 6,665 samples, 2,240 (33.6%) tested positive for HPV. Among the positive cases, single-genotype infections were caused by HPV-16 (14.8%), followed by HPV-18 (2.2%) and clustered high-risk HPV (HR-HPV) genotypes (66.7%). Multiple HPV-16 infections were more common than HPV-18 infections. In addition, 22 cases (1%) presented with infection with HPV-16, HPV-18, and HR-HPV genotypes. A subset of 116 samples from patients with 1 to 2 years of follow-up was analyzed further. Clearance rates were high, at 68.8% for HPV-16 infections and 67.5% for HR-HPV infections. However, the elimination rate of multiple infections with HPV-16 and HR-HPV genotypes was slightly lower, at 55.6%.

Indexed as

CoinfectionHuman papillomavirus 16Human papillomavirus 18Papillomavirus InfectionsUnvaccinated PersonsAdolescentAdultAgedAsymptomatic InfectionsFemaleFollow-Up StudiesGenotypeHumansMiddle AgedPeruPrevalenceGenotypeHuman Papillomavirus virusesPapillomavirus infectionsSexually transmitted diseasesUterine cervical neo-plasms

Identifiers

PMID42143352
PMCPMC13348454

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.