ArticleBMC health services research2026
Study of the direct medical economic burden of patients with healthcare-associated infection based on DRGs matching.
Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundTo discuss the direct economic burden of Healthcare-associated Infection (HAI) in a hospital in Chengdu.
methodsAll patients enrolled in the Diagnosis Related Groups (DRGs) comprehensive evaluation and management system between January 1 and December 31, 2023, were categorized into two groups: those with a Healthcare-associated Infection (HAI) and those without. A 1:1 case matching was performed based on DRG classification, sex, and age (± 5 years). Differences in direct medical costs and length of stay (LOS) between the two groups were compared, followed by a subgroup analysis of infection-related economic burden across diagnostic categories.
resultsThe HAI incidence rate was 0.92%, and the HAI rate per 1,000 patient days was 1.23‰ in 2023. 726 pairs of HAI cases and non-HAI cases were successfully matched. The direct cost of the HAI group was CNY 16,251.63(13244.10 ~ 19259.16) higher than the non-HAI group (1.91 times higher, P < 0.001). The length of hospital stay in the HAI group was 10(8.58 ~ 11.42) days longer (1.71 times higher, P < 0.001), with significant cost increases in treatment fees and Western medicine (P < 0.001). Among all Major Diagnostic Categories (MDCs), the infection and parasitic diseases group incurred the largest economic burden. For HAI patients with sepsis or severe sepsis requiring ≥ 96 h of mechanical ventilation, the total cost was CNY 80,162.31(27439.11 ~ 132885.51) higher than non-HAI patients (P = 0.003), and hospitalization duration increased by 17.5(5.99 ~ 29.01) days (P = 0.003).
conclusionsIn conclusion, implementing scientifically classified DRGs in HAI management provides a strategic framework for advancing precision-oriented healthcare administration.
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