Evidence map›Paper›PMID 42143304›Full record

ArticleBMC health services research2026

Feasibility of mainstreaming schistosomiasis and soil transmitted helminthiasis mass drug administration into primary healthcare: a baseline survey for a community case study in Western Kenya.

Josphat Martin Muchangi, Wyckliff Omondi, Meshack Ndirangu, Carol Karutu, Irene Chami, Gilbert Wangalwa, Chitiavi Juma, Michael Ofire, Robert Ofwete, Kioko Kithuki and 8 more

Registry-linked trialAbstract readControlled Clinical Trial
In one paragraph

Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07507461 (Protocol for a Community Case Study on Integrating Schistosomiasis and Soil-Transmitted Helminthiasis Mass Drug Administration Into Primary Health Care in Western Kenya), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07507461 nacompletednot on this map

Protocol for a Community Case Study on Integrating Schistosomiasis and Soil-Transmitted Helminthiasis Mass Drug Administration Into Primary Health Care in Western Kenya

TypeinterventionalSponsorAmref Health AfricaRan2025 to 2025Enrolled1,229ConditionsSoil Transmitted Helminth (STH) Infections, Schistosomiasis InfectionArmsPrimary Healthcare-Integrated Service Delivery, Standard Mass Drug Adminitsration service delivery
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Josphat Martin MuchangiAmref Health Africa, Nairobi, Kenya. martin.muchangi@amref.org.
Wyckliff OmondiVector-Borne & Neglected Tropical Diseases Unit, Ministry of Health, Nairobi, Kenya.
Meshack NdiranguAmref Health Africa, Nairobi, Kenya.
Carol KarutuThe END Fund, Nairobi, Kenya.
Irene ChamiThe END Fund, Nairobi, Kenya.
Gilbert WangalwaAmref Health Africa, Nairobi, Kenya.
Chitiavi JumaAmref Health Africa, Nairobi, Kenya.
Michael OfireAmref Health Africa, Nairobi, Kenya.
Robert OfweteAmref Health Africa, Nairobi, Kenya.
Kioko KithukiAmref Health Africa, Nairobi, Kenya.
Moses MwamburiReinit Research Limited, Nairobi, Kenya.
Samuel KamauReinit Research Limited, Nairobi, Kenya.
Lenson KariukiVector-Borne & Neglected Tropical Diseases Unit, Ministry of Health, Nairobi, Kenya.
Paul KibatiAmref Health Africa, Nairobi, Kenya.
Japheth AthanasioDepartment of Health Systems Strengthening, Ministry of Health, Nairobi, Kenya.
Geoffrey NjuhiChildren's Investment Fund Foundation, Nairobi, Kenya.
Yvonne OpangaAmref Health Africa, Nairobi, Kenya.
Emmanuel MusombiAmref Health Africa, Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMass drug administration campaigns have enabled great progress in the prevention and control of schistosomiasis and soil transmitted helminthiasis. However, the persistence of these infections continues to challenge public health systems despite decades of control efforts. This study was commissioned to evaluate the feasibility of a transition from periodic mass drug administration campaigns to a sustainable, facility- and community-based delivery model in Western Kenya.

methodsThe study is part of a non-randomized, controlled before-and-after study using a mixed-methods approach. Data were collected from 1,229 households, 24 health facilities (12 control, 12 intervention), focus group discussions, and key informant interviews. The analysis focused on six domains of mainstreaming feasibility: perception of mainstreaming among key stakeholders, processes, infrastructure and system readiness, acceptability and trust for primary healthcare-led treatment, facilitators, and barriers. Finally, we calculated a composite readiness index to grade facility readiness.

resultsGenerally, community perceptions to schistosomiasis and soil-transmitted helminthiasis treatment benefits were found to be high in both the control and intervention groups. Qualitative data showed enhanced trust in the integrated model by virtue of the credibility and professional nature of health facility staff. An overwhelming majority of community members received treatment through household visits (95.5%) implying reliance on periodic MDA at baseline. Community Health Promoters remain a critical source of information on treatment opportunities for low-literacy populations, while media and health facilities are increasingly important among more educated groups. We also found high infrastructural and systemic readiness for treatment mainstreaming with respect to stock availability and data reporting systems. However, stock outs were reported among the facilities. High variability in health worker training coverage suggests a critical challenge in workforce preparedness.

conclusionThe findings point to a strong foundation for mainstreaming but underscore the need for a structured implementation package. Priority actions should include standardized operating procedures, supply chain and digital system strengthening, and expanded Community Health Promoter-led outreach activities to improve consistency, access, and sustainability of deworming services within primary healthcare platforms.

trial registrationRegistration number NCT07507461, prospectively registered on 28th January, 2026.

Indexed as

AnthelminticsHelminthiasisMass Drug AdministrationPrimary Health CareSchistosomiasisAdultFeasibility StudiesFemaleFocus GroupsHumansKenyaMaleSoilAnthelminticsSoilCommunity health workersHealth system mainstreamingKenyaMass drug administrationPrimary healthcareSchistosomiasisSoil-transmitted helminths

Identifiers

PMID42143304
PMCPMC13359928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.