ArticleBMC medical imaging2026
Diagnostic performance of saline-aided ultrasound in the detection of colorectal polyps in children.
Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study aimed to evaluate the diagnostic performance of saline-aided gastroenteric ultrasound (US) for detecting colorectal polyps in pediatric patients.
methodsIn this single-center, retrospective study (April 2018 to November 2023), we analyzed 466 patients with suspected colorectal polyps. All patients underwent conventional US followed by diagnostic colonoscopy. A consecutive paired cohort (n = 292), enrolled after the introduction of a new protocol, additionally received saline-aided US. Diagnostic metrics (accuracy, sensitivity, specificity) and Cohen's kappa were calculated to compare conventional and saline-aided US against histopathological reference standards. Multivariate logistic regression was used to assess clinical parameters affecting diagnostic outcomes.
resultsAmong 466 recruited patients (mean age 4.83 ± 3.12 years, 276 males), 391 were colonoscopy-positive. The most common pathological type was juvenile intestinal polyp (93.1%); the most frequent location was the rectum (59.3%). Saline-aided US was associated with improved diagnostic performance (accuracy: 81.8%, sensitivity: 81.0%, specificity: 85.0%) compared to conventional US (accuracy: 51.4%, sensitivity: 39.6%). Multivariate analysis identified polyp size and location as factors significantly associated with diagnostic outcome (both p < 0.001). For saline-aided US, smaller polyps (< 10 mm) and those located in the rectum (missed diagnosis rate: 22.8%) were associated with higher rates of missed diagnosis.
conclusionSaline-aided US significantly enhances the detection of colorectal polyps in children, demonstrating superior diagnostic accuracy and sensitivity over conventional US.
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