Evidence map›Paper›PMID 42143258›Full record

ArticleBMC nephrology2026

Outcomes of kidney transplants from donors after cardiac arrest; a UK population-based cohort study.

Ffion Dewi, Kamlesh Patel, James Hodson, Dimitra Limnatitou, Christine Biela, Angeliki Kosti, Adnan Sharif, Vasileios K Mavroeidis, Jay Nath

Abstract read
In one paragraph

Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ffion DewiDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.
Kamlesh PatelDepartment of Renal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. kamleshpatel@doctors.org.uk.
James HodsonResearch Development and Innovation Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Dimitra LimnatitouDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.
Christine BielaDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.
Angeliki KostiDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.
Adnan SharifDepartment of Nephrology & Transplantation, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Vasileios K MavroeidisDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.
Jay NathDepartment of Renal Transplantation Surgery, North Bristol NHS Trust, Bristol, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidneys from donation after cardiac arrest (DACA) donors are frequently offered for transplantation in the UK but concerns about organ quality may lead to potential reluctance to accept these kidneys. This study aimed to compare outcomes between DACA and other deceased donor (i.e. non-DACA) kidney recipients.

methodsA retrospective analysis, including multivariable analysis, was conducted of UK national registry data for all deceased donor kidney transplants performed between 2016 and 2020.

resultsData were available for 6,239 donors (of which 43.6% were DACA), and 11,375 recipients. DACA donors were found to be significantly more likely to donate after circulatory death (48.1% vs. 33.5%, p < 0.001) and to have higher terminal creatinine (median: 0.80 vs. 0.71 mg/dL, p < 0.001), but were less likely to be extended criteria donors (29.1% vs. 46.8%, p < 0.001), compared to non-DACA donors. On multivariable analysis, DACA was independently associated with a significantly lower rate of delayed graft function (odds ratio: 0.84, 95% confidence interval [CI]: 0.75-0.94, p = 0.002) and lower 12-month serum creatinine levels (adjusted difference: 2.6%, 95% CI: 1.0-4.2%, p = 0.001), despite higher terminal creatinine. However no significant associations between DACA and patient (p = 0.644) or graft (p = 0.075) survival were observed.

conclusionsThis study found no evidence that DACA is associated with inferior recipient outcomes, with some outcomes even demonstrating a small superiority effect in comparison to non-DACA kidneys. However, these findings can only be interpreted in the context of current organ acceptance practices.

Indexed as

Heart ArrestKidney TransplantationTissue DonorsAdultCohort StudiesDelayed Graft FunctionFemaleGraft SurvivalHumansMaleMiddle AgedRegistriesRetrospective StudiesTissue and Organ ProcurementTreatment OutcomeUnited KingdomDeceased donor kidney transplantationDonation after cardiac arrestDonation after circulatory deathKidney transplant outcomesNational registry studyOrgan acceptance

Identifiers

PMID42143258
PMCPMC13251142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.