ArticleEJNMMI physics2026
Approximate CT-free patient specific attenuation correction method for cardiac-dedicated pinhole CZT system: a feasibility phantom study.
Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMulti-pinhole cardiac-dedicated CZT gamma cameras improve clinical workflow by reducing acquisition duration and/or injected activities. As most of these systems lack integrated CT scanner, attenuation artifacts may appear in the reconstructed image depending on patient morphology. External CT-based attenuation correction is possible but requires manual SPECT-CT registration and increases patient absorbed dose. The aim of the present study was to develop an approach to estimate patient-specific attenuation maps directly from emission data acquired on a pinhole cardiac CZT camera.
methodsTwo anthropomorphic torso phantoms were used. Their heart wall (with or without defects), liver insert and background cavity were filled with
resultsCT-free attenuation maps produced tracer distribution and 17-segment polar maps closely matching those obtained with CT-based attenuation correction. Heart wall defects in the anterior and inferior areas remained clearly visible except for half-obstructive defects. Differences relative to CZT SPECT/CT images were mainly attributable to camera geometry and reconstruction algorithm.
conclusionsThe novel CT-free patient-specific attenuation correction method yields images comparable to CT-based AC images and shows good agreement with AC images from a CZT SPECT/CT system. This approach could enhance the diagnostic performance of current cardiac pinhole CZT cameras without requiring additional CT acquisitions.
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