Evidence map›Paper›PMID 42142191›Full record

ReviewCurrent pain and headache reports2026

Cooled Radiofrequency Ablation of Cervical Nerves for Treating Cervicogenic Headache.

Alaa Abd-Elsayed, Nina Hashimoto, Madelyn Reilly, Barnabas Shiferaw, Lukas Henjum

Abstract readReview
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In one paragraph

Review in Current pain and headache reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alaa Abd-ElsayedAnesthesiology Department, University of Wisconsin, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA. alaaawny@hotmail.com.ORCID http://orcid.org/0000-0002-9890-7860
Nina HashimotoAnesthesiology Department, University of Wisconsin, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA.
Madelyn ReillyAnesthesiology Department, University of Wisconsin, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA.ORCID http://orcid.org/0009-0005-8828-7740
Barnabas ShiferawAnesthesiology Department, University of Wisconsin, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA.ORCID http://orcid.org/0009-0004-2767-6251
Lukas HenjumAnesthesiology Department, University of Wisconsin, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA.ORCID http://orcid.org/0009-0006-2012-2883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical facet arthropathy, a degenerative condition of the facet joints, is a leading cause of cervicogenic headaches. First-line therapies such as physical therapy and pharmacology often fail to provide lasting relief. Cooled radiofrequency ablation (RFA) offers a minimally invasive alternative with potential for significant pain reduction.

objectiveThis retrospective study evaluates the efficacy and safety of cooled RFA for patients with cervicogenic headaches.

methodsThis retrospective analysis consisted of 232 procedures from 137 patients who received cooled RFA of the third occipital nerve (TON) and C3 with/out C4, with/out C5 medial branches, between 2015 and 2025 at UW Health. Data collected include pre- and post-operative pain scores assessed through the Visual Analogue Scale (VAS), duration of pain relief, and adverse events. Paired t-tests were used to analyze the data, with p-values ≤ 0.05 considered statistically significant.

resultsA significant reduction in VAS pain scores was observed (p < 0.001). Pain improvement occurred in 62.2% of procedures, with 18.4% achieving complete remission and 19.4% showing no change in pain. Among effective procedures, the average pain reduction was 58.5 ± 32.2%, with a mean duration of 10.1 ± 8.3 months. Twelve procedures were reported to have self-limiting adverse events that resolved within five months.

conclusionsCooled RFA of cervical medial branches provides effective, durable, and safe pain relief for chronic neck pain and cervicogenic headaches refractory to conservative care. Broader clinical use may benefit from standardized treatment protocols and further study of long-term outcomes.

Indexed as

Post-Traumatic HeadacheRadiofrequency AblationSpinal NervesAdultAgedCervical VertebraeFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesTreatment OutcomeCervical nervesCervicogenic headachesChronic pain managementCooled radiofrequency ablationLong-term pain reliefMinimally invasive procedure

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.